Bone Marrow

PowerPoint presentations:
2015-08-19 Prof. A. Tzankov. Bone marrow biopsies, general remarks (german)
2015-08-26 Prof. A. Tzankov. Granulomatous infections (and reactions) in the bone marrow other than mycobacteria
2015-09-09 Prof. A. Tzankov. Plasma cell neoplasms
2015-09-23 Prof. A. Tzankov. Approaching myeloid neoplasms: diagnostic algorithms
2015-10-07 Prof. A. Tzankov. Reactive changes in the bone marrow
2015-10-21 Prof. A. Tzankov. Bone marrow T-cell infiltrates in viral infections and autoimmune diseases.
2015-10-20 Prof. S. Dirnhofer Myeloproliferative neoplasms
2015-11-10 Prof. S. Dirnhofer Lymphoid infiltrates in bone marrow

Virtual slides:
2015-08-25 Reactive and granulomatous diseases
Serous edema of bone marrow after myeloablative treatment
Pure red cell aplasia after ABO incompatible transplantation
Atypical bone marrow, compatible with azathioprine toxicity
Morbus Paget
Granulomatous myelitis with presence of acid-fast bacilli (mycobacterial myelitis)
Granulomatous myelitis, compatible with sarcoidosis
Relapse of aplastic anemia
Metamizol toxicity
Concentric peritrabecular fibrosis and osteoclast activation , suggestive of hyperparathyreoidism

2015-10-01 Plasma cell neoplasms
Cyclin D1-positive small cell plasma cell myeloma, H&E
Cyclin D1-positive small cell plasma cell myeloma, CD38
Cyclin D1-positive small cell plasma cell myeloma, Cyclin D1
Systemic mastocytosis and lamda-clonal plasmacytoma with amyloidosis, H&E
Systemic mastocytosis and lamda-clonal plasmacytoma with amyloidosis, Kongo
Systemic mastocytosis and lamda-clonal plasmacytoma with amyloidosis, lambda ISH
Systemic mastocytosis and lamda-clonal plasmacytoma with amyloidosis, mast cell tryptase
Hypercellular bone marrow with kappa-clonal plasma cell neoplasia, H&E
Hypercellular bone marrow with kappa-clonal plasma cell neoplasia, CD38
Hypercellular bone marrow with kappa-clonal plasma cell neoplasia, kappa IHC
Plasma cell neoplasia and small lymphocytic lymphoma (SLL), H&E
Plasma cell neoplasia and small lymphocytic lymphoma (SLL), Giemsa
Plasma cell neoplasia and small lymphocytic lymphoma (SLL), CD20
Plasma cell neoplasia and small lymphocytic lymphoma (SLL), CD23
Plasma cell neoplasia and small lymphocytic lymphoma (SLL), CD38
Plasma cell neoplasia and small lymphocytic lymphoma (SLL), kappa&lambda IHC

2015-10-05 Myeloid neoplasms
Acute myelogenous leukemia compatible with promyelocytic leukemia
Myeloid neoplasia with eosinophilia and rearrangement of PDGFR-Alpha gene
Systemic mastocytosis
Myeloid and lymphoid neoplasm with eosinophilia and recurrent genetic abnormalities of PDGFR-alpha-, PDGFR-beta- or FGFR1-gene
Refractory anemia with multilineage dysplasia and excess of blasts type 2
Therapy-associated myelodysplastic syndrome
Myelodysplasia-associated acute myelogenous leukemia without differentiation (M1)
Acute monoblastic/monocytic leukemia

2015-10-27 Myeloproliferative neoplasms
Myeloproliferative neoplasm compatible with essential thrombocythaemia
Primary myelofibrosis (PMF)
Polycythaemia vera with myelofibrosis grade 1

2015-11-10 Lymphoid infiltrates in bone marrow
Nodular and beginning diffuse infiltration by chronic lymphatic leukemia (CLL)
Nodular and beginning diffuse infiltration by CLL: CD20
Nodular and beginning diffuse infiltration by CLL: CD5
Nodular and beginning diffuse infiltration by CLL: CD23
Interstitial and nodular infiltration by a mantle cell lymphoma
Interstitial and nodular infiltration by a mantle cell lymphoma: Cyclin D1
Peritrabecular and diffuse infiltration by a follicular lymphoma
Peritrabecular and diffuse infiltration by a follicular lymphoma: CD20
Diffuse infiltration by acute lymphoblastic leukemia (T-ALL)
Diffuse infiltration by T-ALL: TdT

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